Correlation to FVIII:C in two thrombin generation tests: TGA-CAT and INNOVANCE ETP
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چکیده
منابع مشابه
Correlation to FVIII:C in Two Thrombin Generation Tests: TGA-CAT and INNOVANCE ETP
Introduction Several thrombin-generation tests are available, but few have been directly compared. Our primary aim was to investigate the correlation of two thrombin generation tests, thrombin generation assay-calibrated automated thrombogram (TGA-CAT) and INNOVANCE ETP, to factor VIII levels (FVIII:C) in a group of patients with hemophilia A. The secondary aim was to investigate inter-laborato...
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BACKGROUND Low molecular weight heparins (LMWH's) are used to prevent and treat thrombosis. Tests for monitoring LMWH's include anti-factor Xa (anti-FXa), activated partial thromboplastin time (aPTT) and thrombin generation. Anti-FXa is the current gold standard despite LMWH's varying affinities for FXa and thrombin. AIM To examine the effects of two different LMWH's on the results of 4 diffe...
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Thrombin generation was studied in paediatric patients with congenital heart disease (CHD) undergoing cardiac surgery using the calibrated automated thrombography (CAT) in terms of the lag time until the onset of thrombin formation, time to thrombin peak maximum (TTP), endogenous thrombin potential (ETP), and thrombin peak height. The suitability to determine the coagulation status of these pat...
متن کاملDeterminants of the APTT- and ETP-based APC sensitivity tests.
BACKGROUND A reduced sensitivity for activated protein C (APC) is associated with an increased risk of venous thrombosis even in the absence of the factor (F)V Leiden mutation. This risk has been demonstrated with two APC sensitivity tests, which quantify the effects of APC on the activated partial thromboplastin time (APTT) and the endogenous thrombin potential (ETP), respectively. OBJECTIVE...
متن کاملThrombin generation and rotational thromboelastometry in the healthy adult population.
AIM Published data on thrombin generation variables and their correlation with thromboelastometry in the healthy population are scarce. This study aimed at assessing thrombin generation in adults and its correlation to classical rotational thromboelastometry (ROTEM). METHODS Thrombin generation was measured in platelet-poor plasma from healthy volunteers using the calibrated automated thrombo...
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ژورنال
عنوان ژورنال: Mediterranean Journal of Hematology and Infectious Diseases
سال: 2017
ISSN: 2035-3006
DOI: 10.4084/mjhid.2017.064